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ST-1535
CAS No. 496955-42-1
ST-1535( ST 1535 | ST1535 )
Catalog No. M14663 CAS No. 496955-42-1
A potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 129 | Get Quote |
|
| 10MG | 176 | Get Quote |
|
| 25MG | 306 | Get Quote |
|
| 50MG | 444 | Get Quote |
|
| 100MG | 647 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameST-1535
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
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DescriptionA potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM; displays 10, 58 and >160-fold selectivity over A1, A2B and A3 receptors, respectively; increases locomotor activity in animal models of Parkinson s disease.
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In Vitro——
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In VivoAnimal Model:5-6 weeks CD1 male mice Dosage:0, 5, 10 mg/kg Administration:P.o.Result:Antagonized catalepsy induced by i.c.v. administration with the A2A adenosine agonist CGS 21680.Animal Model:Male Sprague Dawley rats Dosage:10, 20, 40mg/kg Administration:I.p. Result:Significantly increased the number of contralateral turns induced by l-DOPA (3 mg/kg i.p.) at 20 and 40 mg/kg.
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SynonymsST 1535 | ST1535
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PathwayApoptosis
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TargetAdenosine Receptor
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RecptorAdenosine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number496955-42-1
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Formula Weight272.316
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Molecular FormulaC12H16N8
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Purity>98% (HPLC)
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Solubility——
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SMILESNC1=C2N=C(N3N=CC=N3)N(C)C2=NC(CCCC)=N1
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Chemical Name2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Minetti P, et al. J Med Chem. 2005 Nov 3;48(22):6887-96.
2. Rose S, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):82-7.
3. Rose S, et al. Brain Res. 2007 Feb 16;1133(1):110-4.
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