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WAY-200070

CAS No. 440122-66-7

WAY-200070( WAY200070 | WAY 200070 )

Catalog No. M14497 CAS No. 440122-66-7

WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 59 In Stock
2MG 33 In Stock
5MG 53 In Stock
10MG 92 In Stock
25MG 188 In Stock
50MG 305 In Stock
100MG 492 In Stock
200MG 700 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    WAY-200070
  • Note
    Research use only, not for human use.
  • Brief Description
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).
  • Description
    WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM); induces galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain, causes and learn the socially acquired preferenc in mice, deonstrates the anxiolytic-like and antidepressant-like effects in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    WAY200070 | WAY 200070
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    ERRα|ERRβ
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    440122-66-7
  • Formula Weight
    306.11152
  • Molecular Formula
    C13H8BrNO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 31 mg/mL
  • SMILES
    O=C1C=C/C(C=C1)=C2OC3=C(Br)C=C(O)C=C3N/2
  • Chemical Name
    5-Benzoxazolol, 7-bromo-2-(4-hydroxyphenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hughes ZA, et al. Neuropharmacology. 2008 Jun;54(7):1136-42. 2. Clipperton AE, et al. Neuropsychopharmacology. 2008 Sep;33(10):2362-75. 3. Malamas MS, et al. J Med Chem. 2004 Oct 7;47(21):5021-40.
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