IBMX

CAS No. 28822-58-4

IBMX( Isobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine )

Catalog No. M13880 CAS No. 28822-58-4

3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
25MG 31 In Stock
50MG 44 In Stock
100MG 54 In Stock
200MG 98 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    IBMX
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.
  • Description
    3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates cyclic nucleotide regulated protein kinases.(In Vitro):IBMX (0.5 mM) induces neural-like cells for neural differentiation of cord blood derived mesenchymal-like stem cells.IBMX induces initiation of the differentiation of programpre-adipocytes.IBMX (500 μM) induces neuronal differentiation of small cell lung cancer.IBMX (100 μM) induces differentiation of 3T3-LI adipocytes.IBMX (500 μM) induces adipose tissue-derived stem cells (ADSC) differentiate into neuron-like cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Isobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE3| PDE4| PDE5
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    28822-58-4
  • Formula Weight
    222.24
  • Molecular Formula
    C10H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in DMSO
  • SMILES
    O=C(N1C)N(CC(C)C)C2=C(NC=N2)C1=O
  • Chemical Name
    3-Isobutyl-1-methylxanthine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jin KS, et al. Food Chem Toxicol. 2014 Jun;68:38-43.
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