IBMX
CAS No. 28822-58-4
IBMX( Isobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine )
Catalog No. M13880 CAS No. 28822-58-4
3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 25MG | 31 | In Stock |
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| 50MG | 44 | In Stock |
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| 100MG | 54 | In Stock |
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| 200MG | 98 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIBMX
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NoteResearch use only, not for human use.
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Brief Description3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.
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Description3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates cyclic nucleotide regulated protein kinases.(In Vitro):IBMX (0.5 mM) induces neural-like cells for neural differentiation of cord blood derived mesenchymal-like stem cells.IBMX induces initiation of the differentiation of programpre-adipocytes.IBMX (500 μM) induces neuronal differentiation of small cell lung cancer.IBMX (100 μM) induces differentiation of 3T3-LI adipocytes.IBMX (500 μM) induces adipose tissue-derived stem cells (ADSC) differentiate into neuron-like cells.
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In Vitro——
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In Vivo——
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SynonymsIsobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE3| PDE4| PDE5
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number28822-58-4
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Formula Weight222.24
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Molecular FormulaC10H14N4O2
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESO=C(N1C)N(CC(C)C)C2=C(NC=N2)C1=O
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Chemical Name3-Isobutyl-1-methylxanthine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Propentofylline
Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's disease, vascular dementia, cognitive impairment, dementia, and chronic pain.
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Resibufogenin
Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.
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Isomazole
Isomazole is a novel orally available phosphodiesterase (PDE) inhibitor with calcium-sensitizing properties that inhibits PDE3 and PDE4.
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