Resibufogenin

CAS No. 465-39-4

Resibufogenin( RBG | Bufotenine | Resibufogenin )

Catalog No. M18571 CAS No. 465-39-4

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 111 In Stock
5MG 101 In Stock
10MG 155 In Stock
25MG 282 In Stock
50MG 461 In Stock
100MG 644 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Resibufogenin
  • Note
    Research use only, not for human use.
  • Brief Description
    Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.
  • Description
    Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    RBG | Bufotenine | Resibufogenin
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    Others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    465-39-4
  • Formula Weight
    384.51
  • Molecular Formula
    C24H32O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 260.07 mM
  • SMILES
    CC12CCC(CC1CCC3C2CCC4(C35C(O5)CC4C6=COC(=O)C=C6)C)O
  • Chemical Name
    14,15beta-Epoxy-3beta-hydroxy-5beta-bufa-20,22-dienolide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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