iNOS inhibitor 12
CAS No. 268730-08-1
iNOS inhibitor 12( —— )
Catalog No. M13822 CAS No. 268730-08-1
iNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameiNOS inhibitor 12
-
NoteResearch use only, not for human use.
-
Brief DescriptioniNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM.
-
DescriptioniNOS inhibitor 12 is a potent, highly selective iNOS inhibitor with IC50 of 79 nM, dispalys almost 100-fold selectivity over eNOS and nNOS.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetNOS
-
RecptorNOS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number268730-08-1
-
Formula Weight336.395
-
Molecular FormulaC19H20N4O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-(4-((4-methoxypyridin-2-yl)amino)piperidine-1-carbonyl)benzonitrile
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Garcin ED, et al. Nat Chem Biol. 2008 Nov;4(11):700-7.
2. Connolly S, et al. J Med Chem. 2004 Jun 3; 47(12):3320-3.
molnova catalog
related products
-
L-NMMA acetate
L-NMMA acetate is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3).
-
MEG hemisulfate
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS in tissue homogenates.
-
Epibetulinic acid
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.
Cart
sales@molnova.com