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Cinepazide maleate
CAS No. 26328-04-1
Cinepazide maleate( —— )
Catalog No. M13807 CAS No. 26328-04-1
A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 45 | In Stock |
|
| 50MG | 59 | In Stock |
|
| 100MG | 101 | In Stock |
|
| 200MG | 178 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCinepazide maleate
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NoteResearch use only, not for human use.
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Brief DescriptionA cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.
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DescriptionA cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.Ischemia Approved(In Vitro):Cinepazide Maleate (intravenous injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide Maleate (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner in dogs.
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In Vitro——
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In VivoCinepazide Maleate (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide Maleate (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner?in dogs.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCardiovascular Disease
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IndicationIschemia
Chemical Information
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CAS Number26328-04-1
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Formula Weight533.5708
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Molecular FormulaC26H35N3O9
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCOC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCN(CC2)CC(=O)N3CCCC3.C(=C\C(=O)O)\C(=O)O
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Chemical NamePiperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (E)-, (2Z)-2-butenedioate (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Miwa S, et al. Jpn J Pharmacol. 1986 May;41(1):109-15.
2. Zhao J, et al. Neurol Sci. 2014 Jun;35(6):875-81.
3. Li Y, et al. Biol Pharm Bull. 2017 Mar 1;40(3):249-255.
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