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Cinepazide maleate

CAS No. 26328-04-1

Cinepazide maleate( —— )

Catalog No. M13807 CAS No. 26328-04-1

A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
100MG 27 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Cinepazide maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.
  • Description
    A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.Ischemia Approved(In Vitro):Cinepazide Maleate (intravenous injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide Maleate (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner in dogs.
  • In Vitro
    ——
  • In Vivo
    Cinepazide Maleate (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide Maleate (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner?in dogs.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    Ischemia

Chemical Information

  • CAS Number
    26328-04-1
  • Formula Weight
    533.5708
  • Molecular Formula
    C26H35N3O9
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCN(CC2)CC(=O)N3CCCC3.C(=C\C(=O)O)\C(=O)O
  • Chemical Name
    Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (E)-, (2Z)-2-butenedioate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Miwa S, et al. Jpn J Pharmacol. 1986 May;41(1):109-15. 2. Zhao J, et al. Neurol Sci. 2014 Jun;35(6):875-81. 3. Li Y, et al. Biol Pharm Bull. 2017 Mar 1;40(3):249-255.
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