Povidone-iodine
CAS No. 25655-41-8
Povidone-iodine ( (PVP-I) )
Catalog No. M13774 CAS No. 25655-41-8
Povidone-iodine is an iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePovidone-iodine
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NoteResearch use only, not for human use.
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Brief DescriptionPovidone-iodine is an iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.
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DescriptionPovidone-iodine is an iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.(In Vitro):MIC values of Povidone iodine (iodopovidone) (PVP-I) are 31.25 mg/L and 7.82 mg/L, respectively. Treatment of the cells with Povidone iodine (PVP-I) at a dilution of 1:32 causes a sharp reduction in cell viability by 90-95% on all testing cell lines.(In Vivo):The Dp+Povidone iodine (iodopovidone) (PVP-I) group has the second highest average score from day 13 to the end of the experimental period. The Dp+Povidone iodine and Dp+Et-OH groups also show a significantly increase in eosinophil count compare with the control group (p<0.05 and p<0.001, respectively). However, the eosinophil count does not significantly differ among the Dp+Povidone iodine (PVP-I), Dp+CHG, and Dp+vehicle groups.
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In VitroMIC values of Povidone iodine (iodopovidone) (PVP-I) are 31.25 mg/L and 7.82 mg/L, respectively. Treatment of the cells with Povidone iodine (PVP-I) at a dilution of 1:32 causes a sharp reduction in cell viability by 90-95% on all testing cell lines.
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In VivoThe Dp+Povidone iodine (iodopovidone) (PVP-I) group has the second highest average score from day 13 to the end of the experimental period. The Dp+Povidone iodine and Dp+Et-OH groups also show a significantly increase in eosinophil count compare with the control group (p<0.05 and p<0.001, respectively). However, the eosinophil count does not significantly differ among the Dp+Povidone iodine (PVP-I), Dp+CHG, and Dp+vehicle groups.
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Synonyms(PVP-I)
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number25655-41-8
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Formula Weight364.95
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Molecular FormulaC6H9I2NO
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCCC(C)N1CCCC1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Akcay E, et al. Childs Nerv Syst. 2012, 28(12):2071-5.
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