ASC-JM-17

Research use only, not for human use.

ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones.

ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.

——

——

——

Others

Other Targets

Others

——

——

1039760-91-2

464.55

C28H32O6

>98% (HPLC)

——

C(CC1CCC1)(C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C(/C=C/C3=CC(OC)=C(OC)C=C3)=O

——

(-20℃)

With Ice Pack

≥ 2 years