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Emricasan
CAS No. 254750-02-2
Emricasan( IDN-6556 | PF-03491390 )
Catalog No. M13761 CAS No. 254750-02-2
Emricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 98 | In Stock |
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| 2MG | 48 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 133 | In Stock |
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| 25MG | 240 | In Stock |
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| 50MG | 390 | In Stock |
|
| 100MG | 574 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEmricasan
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NoteResearch use only, not for human use.
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Brief DescriptionEmricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.
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DescriptionEmricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.Steatohepatitis Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsIDN-6556 | PF-03491390
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PathwayApoptosis
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TargetCaspase
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RecptorCaspase
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number254750-02-2
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Formula Weight569.51
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Molecular FormulaC26H27F4N3O7
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Purity>98% (HPLC)
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SolubilityDMSO: 93 mg/mL (163.3 mM); Ethanol: 93 mg/mL (163.3 mM); Water: <1 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(O)C[C@H](NC([C@H](C)NC(C(NC1=CC=CC=C1C(C)(C)C)=O)=O)=O)C(COC2=C(F)C(F)=CC(F)=C2F)=O
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Chemical Name(3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xu M, et al. Nat Med. 2016 Oct;22(10):1101-1107.
2. Brumatti G, et al. Sci Transl Med. 2016 May 18;8(339):339ra69.
3. McCall MD, et al. Transplantation. 2012 Jul 15;94(1):30-5.
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