Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - Aminopeptidase - Beloranib

Beloranib

CAS No. 251111-30-5

Beloranib( CKD-732 | ZGN-433 | ZGN-440 )

Catalog No. M13740 CAS No. 251111-30-5

An analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 2583 Get Quote
50MG 5202 Get Quote
100MG 7380 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Beloranib
  • Note
    Research use only, not for human use.
  • Brief Description
    An analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor.
  • Description
    An analog of the natural compound Fumagillin that functions as a highly potent methionine aminopeptidase 2 (MetAP2) inhibitor; strongly inhibit the growth of cancers in xenografted nude model; also causes significant body weight and appetite reduction an anti-obesity agent.Obesity Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CKD-732 | ZGN-433 | ZGN-440
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Aminopeptidase
  • Recptor
    Aminopeptidase
  • Research Area
    Metabolic Disease
  • Indication
    Obesity

Chemical Information

  • CAS Number
    251111-30-5
  • Formula Weight
    499.65
  • Molecular Formula
    C29H41NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O[C@H](CC1)[C@@H](OC)[C@H]([C@@]2(C)O[C@@H]2C/C=C(C)\C)[C@]31CO3)/C=C/C4=CC=C(OCCN(C)C)C=C4
  • Chemical Name
    [(3R,6R,7S,8S)-7-methoxy-8-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]octan-6-yl] (E)-3-[4-[2-(dimethylamino)ethoxy]phenyl]prop-2-enoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim YM, et al. J Mol Endocrinol. 2007 Apr;38(4):455-65. 2. Morgen M, et al. ACS Chem Biol. 2016 Apr 15;11(4):1001-11. 3. Chun E, et al. Int J Cancer. 2005 Mar 10;114(1):124-30. 4. Hughes TE, et al. Obesity (Silver Spring). 2013 Sep;21(9):1782-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • DG051

    A potent, selective LTA4H (Leukotriene A4 hydrolase) inhibitor (IC50/Kd=47/25 nM) of leukotriene B4 biosynthesis.

  • ARM1

    ARM1 is a potent inhibitor of aminopeptidase and epoxide hydrolase. The IC50 values are 7.61 μM for aminopeptidase and 12.4 μM for epoxide hydrolase.

  • JNJ-26993135

    JNJ-26993135 is a potent, selective leukotriene A4 hydrolase (LTA4H) inhibitor.

Sign In Join Free