Home - Products - Endocrinology/Hormones - AChR - Catharanthine

Catharanthine

CAS No. 2468-21-5

Catharanthine( (+)-3,4-Didehydrocoronaridine )

Catalog No. M13718 CAS No. 2468-21-5

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	48	In Stock
50MG	36	In Stock
100MG	53	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Catharanthine
Note

Research use only, not for human use.
Brief Description

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
Description

Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
In Vitro

——
In Vivo

Animal Model:13-week-old male SpragueDawley rats (300-350 g) Dosage:0.5-20 mg/kg Administration:IV; single dose Result:Evoked rapid, transient reductions in BP and HR (lasting ,2 minutes) at low doses (0.5–5 mg/kg), whereas at higher doses (10 and 20 mg/kg), the BP and HR reductions were sustained.
Synonyms

(+)-3,4-Didehydrocoronaridine
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

nAChR
Research Area

Neurological Disease
Indication

——

Chemical Information

CAS Number

2468-21-5
Formula Weight

336.42
Molecular Formula

C21H24N2O2
Purity

>98% (HPLC)
Solubility

Ethanol: 3 mg/mL (8.91 mM); DMSO: 67 mg/mL (199.14 mM)
SMILES

CCC1=C[C@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pereira DM, et al. Phytomedicine, 2010, 17(8-9), 646-652.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

yangonin

Yangonin is a novel CB? receptor ligand, it exhibits affinity for the human recombinant CB? receptor.
Encenicline

Encenicline is a selective α7 nicotinic acetylcholine receptor?(nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.
6-Ethoxydihydrosangu...

6-Ethoxydihydrosanguinarine shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/- 0.19 microM, respectively.

Sign In Join Free