Imidafenacin( ONO-8025 | KRP-197 )

Catalog No. M19789 CAS No. 170105-16-5

Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.

Purity : >98% (HPLC)

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Biological Information

Product Name

Imidafenacin
Note

Research use only, not for human use.
Brief Description

Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.
Description

Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.
In Vitro

——
In Vivo

——
Synonyms

ONO-8025 | KRP-197
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

mAChR
Research Area

Neurological Disease
Indication

Chronic obstructive pulmonary disease

Chemical Information

CAS Number

170105-16-5
Formula Weight

319.4
Molecular Formula

C20H21N3O
Purity

>98% (HPLC)
Solubility

DMSO:7.8 mg/mL (24.42 mM) Need ultrasonic and warming
SMILES

Cc1nccn1CCC(C(N)=O)(c1ccccc1)c1ccccc1
Chemical Name

4-(2-Methyl-1-imidazolyl)-22-diphenylbutanamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yamazaki T et al. Imidafenacin has no influence on learning in nucleus basalis of Meynert-lesioned rats. Naunyn Schmiedebergs Arch Pharmacol. 2013 Dec;386(12):1095-102.

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