Cart
sales@molnova.com
Flopropione
CAS No. 2295-58-1
Flopropione( —— )
Catalog No. M13637 CAS No. 2295-58-1
Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
|
| 200MG | 52 | In Stock |
|
| 500MG | 86 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFlopropione
-
NoteResearch use only, not for human use.
-
Brief DescriptionFlopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.
-
DescriptionFlopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist(In Vivo):The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.
-
In Vitro——
-
In VivoThe effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor5-HT1A
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number2295-58-1
-
Formula Weight182.18
-
Molecular FormulaC9H10O4
-
Purity>98% (HPLC)
-
SolubilityEthanol: 36 mg/mL (197.61 mM); DMSO: 36 mg/mL (197.61 mM)
-
SMILESCCC(=O)C1=C(O)C=C(O)C=C1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Hyperforin
Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels and triggers adipose tissue thermogenesis via the Dlat-AMPK signaling axis to suppress obesity. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod -induced psoriasis-like mice model.
-
XEN-445
XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.
-
CJ 033466
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.
