Flopropione

Research use only, not for human use.

Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist.

Flopropione is a spasmolytic or antispasmodic agent, and acts as a 5-HT1A receptor antagonist(In Vivo):The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.

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The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems.

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Endocrinology/Hormones

5-HT Receptor

5-HT1A

Neurological Disease

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2295-58-1

182.18

C9H10O4

>98% (HPLC)

Ethanol: 36 mg/mL (197.61 mM); DMSO: 36 mg/mL (197.61 mM)

CCC(=O)C1=C(O)C=C(O)C=C1O

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(-20℃)

With Ice Pack

≥ 2 years