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AZD3229
CAS No. 2248003-60-1
AZD3229( AZD-3229 | AZD 3229 )
Catalog No. M13614 CAS No. 2248003-60-1
AZD3229 (AZD-3229) is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 95 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 136 | In Stock |
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| 25MG | 247 | In Stock |
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| 50MG | 356 | In Stock |
|
| 100MG | 498 | In Stock |
|
| 200MG | 684 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZD3229
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NoteResearch use only, not for human use.
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Brief DescriptionAZD3229 (AZD-3229) is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM).
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DescriptionAZD3229 (AZD-3229) is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM); shows good margin to KDR-driven effects, also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V).
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In Vitro——
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In Vivo——
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SynonymsAZD-3229 | AZD 3229
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PathwayAngiogenesis
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Targetc-Kit
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RecptorKit
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Research Area——
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Indication——
Chemical Information
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CAS Number2248003-60-1
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Formula Weight479.516
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Molecular FormulaC24H26FN7O3
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Purity>98% (HPLC)
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SolubilityDMSO: 95 mg/mL (198.12 mM); Water: Insoluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(NC1=CC=C(NC2=C3C(F)=CC(OCCOC)=CC3=NC=N2)C=C1)CN4N=NC(C(C)C)=C4
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Chemical NameN-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]-amino}phenyl)-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]-acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kettle JG, et al. J Med Chem. 2018 Sep 24. doi: 10.1021/acs.jmedchem.8b00938.
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