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UNC-2170 maleate

CAS No. 2173992-60-2

UNC-2170 maleate( UNC2170 maleate )

Catalog No. M13477 CAS No. 2173992-60-2

A small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    UNC-2170 maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
  • Description
    A small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain; highly cell permeant with no significant measureable cellular efflux; shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    UNC2170 maleate
  • Pathway
    Apoptosis
  • Target
    MDM2-p53
  • Recptor
    MDM2-p53
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2173992-60-2
  • Formula Weight
    429.3
  • Molecular Formula
    C18H25BrN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-bromo-N-(3-(tert-butylamino)propyl)benzamide maleate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.
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