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KUNG94
CAS No. 2134571-29-0
KUNG94( KUNG-94 | KUNG 94 )
Catalog No. M13400 CAS No. 2134571-29-0
A potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
|
| 50MG | 1782 | In Stock |
|
| 100MG | 2250 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKUNG94
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α.
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DescriptionA potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α; shows antiproliferative activity against RPMI8226 cells with Gi50 of 1.4 uM, reduces LRP6 levels and induces apoptosis.
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In Vitro——
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In Vivo——
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SynonymsKUNG-94 | KUNG 94
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP
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Research Area——
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Indication——
Chemical Information
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CAS Number2134571-29-0
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Formula Weight363.388
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Molecular FormulaC22H18FNO3
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Purity>98% (HPLC)
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Solubility——
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SMILESFC1=CC=C(CC2=C(O)C=C(O)C(C(N3CC(C=CC=C4)=C4C3)=O)=C2)C=C1
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Chemical Name(5-(4-fluorobenzyl)-2,4-dihydroxyphenyl)(isoindolin-2-yl)methanone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018.
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