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Rpn11 inhibitor 35
CAS No. 2084868-04-0
Rpn11 inhibitor 35( —— )
Catalog No. M13249 CAS No. 2084868-04-0
Rpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 126 | In Stock |
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| 2MG | 56 | In Stock |
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| 5MG | 91 | In Stock |
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| 10MG | 145 | In Stock |
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| 25MG | 300 | In Stock |
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| 50MG | 504 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRpn11 inhibitor 35
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NoteResearch use only, not for human use.
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Brief DescriptionRpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM.
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DescriptionRpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM,100-fold selectivity over Csn5 and 10-fold selectivity over AMSH; inhibits 293T and A549 cells proliferation with IC50 of 2.1 and 3.8 uM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetProteasome
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RecptorProteasome
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number2084868-04-0
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Formula Weight628.802
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Molecular FormulaC30H24N6O2S4
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 55.67 mg/mL 88.53 mM
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SMILESC1=CC2=CC(=CN=C2C(=C1)SSC3=CC=CC4=CC(=CN=C43)C(=O)NCCC5=NC=CS5)C(=O)NCCC6=NC=CS6
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Chemical Name8,8'-disulfanediylbis(N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Perez C, et al. J Med Chem. 2017 Feb 23;60(4):1343-1361.
2. Li J, et al. Nat Chem Biol. 2017 May;13(5):486-493.
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