OSSK-674842( OSSK-2 | OSSK 674842 )

Catalog No. M13188 CAS No. 2054944-80-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

OSSK-674842
Note

Research use only, not for human use.
Brief Description

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
Description

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.Cystic Fibrosis Preclinical.
In Vitro

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In Vivo

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Synonyms

OSSK-2 | OSSK 674842
Pathway

Apoptosis
Target

CFTR
Recptor

CFTR
Research Area

Other Indications
Indication

Fibrosis

CAS Number

2054944-80-6
Formula Weight

457.122
Molecular Formula

C16H15Br2N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(N/N=C/C(C=C(Br)C(O)=C1Br)=C1O)CNC2=CC=C(C)C=C2
Chemical Name

(E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide

1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.

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