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Pomalidomide
CAS No. 19171-19-8
Pomalidomide( CC-4047 | CC4047 | CC 4047 )
Catalog No. M13004 CAS No. 19171-19-8
A potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 54 | In Stock |
|
| 10MG | 49 | In Stock |
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| 50MG | 73 | In Stock |
|
| 100MG | 94 | In Stock |
|
| 200MG | 103 | In Stock |
|
| 500MG | 120 | In Stock |
|
| 1G | 156 | In Stock |
|
Biological Information
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Product NamePomalidomide
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NoteResearch use only, not for human use.
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Brief DescriptionA potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.
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DescriptionA potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs; upregulates interferon gamma, IL-2 and IL-10.Blood Cancer Approved.
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In Vitro——
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In Vivo——
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SynonymsCC-4047 | CC4047 | CC 4047
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PathwayApoptosis
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TargetTNF
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RecptorTNF-α
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number19171-19-8
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Formula Weight273.2441
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Molecular FormulaC13H11N3O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
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Chemical Name1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Muller GW, et al. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30.
2. Payvandi F, et al. Cell Immunol. 2004 Aug;230(2):81-8.
3. Galustian C, et al. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45.
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