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Pomalidomide

CAS No. 19171-19-8

Pomalidomide( CC-4047 | CC4047 | CC 4047 )

Catalog No. M13004 CAS No. 19171-19-8

A potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 54 In Stock
10MG 49 In Stock
50MG 73 In Stock
100MG 94 In Stock
200MG 103 In Stock
500MG 120 In Stock
1G 156 In Stock
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Biological Information

  • Product Name
    Pomalidomide
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.
  • Description
    A potent inhibitor of TNF-α production; inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs; upregulates interferon gamma, IL-2 and IL-10.Blood Cancer Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CC-4047 | CC4047 | CC 4047
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α
  • Research Area
    Cancer
  • Indication
    Blood cancer

Chemical Information

  • CAS Number
    19171-19-8
  • Formula Weight
    273.2441
  • Molecular Formula
    C13H11N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
  • Chemical Name
    1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Muller GW, et al. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1625-30. 2. Payvandi F, et al. Cell Immunol. 2004 Aug;230(2):81-8. 3. Galustian C, et al. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45.
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