Bremelanotide
CAS No. 189691-06-3
Bremelanotide( PT-141 | PT 141 )
Catalog No. M12979 CAS No. 189691-06-3
A peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBremelanotide
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NoteResearch use only, not for human use.
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Brief DescriptionA peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction.
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DescriptionA peptide, non-selective melanocortin receptor agonist for treatment for female sexual dysfunction; selectively stimulates solicitational behaviors in the female rat, without affecting lordosis, pacing, or other sexual behaviors, does not cause generalized motor activation; a peptide analogue of α-MSH.Sexual Dysfunction Phase 3 Clinical.
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In Vitro——
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In Vivo——
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SynonymsPT-141 | PT 141
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PathwayGPCR/G Protein
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TargetMelanocortin Receptor
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RecptorMelanocortin Receptor
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Research AreaEndocrinology
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IndicationSexual Dysfunction
Chemical Information
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CAS Number189691-06-3
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Formula Weight1025.2
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Molecular FormulaC50H68N14O10
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C
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Chemical NameN-Acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysine (2-7)-lactam
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Setmelanotide Acetat...
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
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Nonapeptide-1 acetat...
Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM.
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[D-Trp8]-γ-MSH
Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammatory efficacy.
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