Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - Guanylate Cyclase - MGV354

MGV354

CAS No. 1852495-86-3

MGV354( MGV 354 | MGV-354 )

Catalog No. M12863 CAS No. 1852495-86-3

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 126 In Stock
5MG 93 In Stock
10MG 159 In Stock
25MG 321 In Stock
50MG 443 In Stock
100MG 631 In Stock
200MG 849 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    MGV354
  • Note
    Research use only, not for human use.
  • Brief Description
    MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.
  • Description
    MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.Other Indication Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MGV 354 | MGV-354
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Guanylate Cyclase
  • Recptor
    Guanylate Cyclase
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    1852495-86-3
  • Formula Weight
    575.713
  • Molecular Formula
    C35H37N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (173.70 mM)
  • SMILES
    ——
  • Chemical Name
    (S)-1-(6-(3-((4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Prasanna G, et al. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1704-1716.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Nelociguat

    Nelociguat(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.

  • Vericiguat

    Vericiguat (0.01 μM to 100 μM) stimulates recombinant sGC concentration dependently, by 1.7-fold to 57.6-fold.

  • Plecanatide

    Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.

Sign In Join Free