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MGV354
CAS No. 1852495-86-3
MGV354( MGV 354 | MGV-354 )
Catalog No. M12863 CAS No. 1852495-86-3
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 126 | In Stock |
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| 5MG | 93 | In Stock |
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| 10MG | 159 | In Stock |
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| 25MG | 321 | In Stock |
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| 50MG | 443 | In Stock |
|
| 100MG | 631 | In Stock |
|
| 200MG | 849 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMGV354
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NoteResearch use only, not for human use.
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Brief DescriptionMGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.
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DescriptionMGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.Other Indication Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsMGV 354 | MGV-354
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PathwayMetabolic Enzyme/Protease
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TargetGuanylate Cyclase
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RecptorGuanylate Cyclase
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number1852495-86-3
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Formula Weight575.713
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Molecular FormulaC35H37N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (173.70 mM)
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SMILES——
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Chemical Name(S)-1-(6-(3-((4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Prasanna G, et al. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1704-1716.
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