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PST-1P

CAS No. 1801769-45-8

PST-1P( —— )

Catalog No. M12745 CAS No. 1801769-45-8

PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PST-1P
  • Note
    Research use only, not for human use.
  • Brief Description
    PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
  • Description
    PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines; 100-fold more cytotoxic than in the dark; induces mitotic arrest and cell death in a light-dependent manner, and controls mitosis and the microtubule cytoskeleton in mammalian tissue in vivo; highly water-soluble prodrug of PST-1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Microtubule/Tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1801769-45-8
  • Formula Weight
    398.308
  • Molecular Formula
    C16H19N2O8P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (Z)-2-methoxy-5-((3,4,5-trimethoxyphenyl)diazenyl)phenyl dihydrogen phosphate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Borowiak M, et al. Cell. 2015 Jul 16;162(2):403-11.
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