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HIF2α-IN-1
CAS No. 1799948-06-3
HIF2α-IN-1( HIF-2alpha IN-1 | HIF 2alpha-IN-1 | HIF-2alpha-IN-1 )
Catalog No. M12731 CAS No. 1799948-06-3
A potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 357 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHIF2α-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionA potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay.
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DescriptionA potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay.
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In Vitro——
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In Vivo——
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SynonymsHIF-2alpha IN-1 | HIF 2alpha-IN-1 | HIF-2alpha-IN-1
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorHIF/HIF Prolyl-hydroxylase
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number1799948-06-3
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Formula Weight405.2961
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Molecular FormulaC16H8F5NO4S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESN#CC1=CC(F)=CC(OC2=CC=C3C([C@@H](O)C(F)(F)S3(=O)=O)=C2C(F)F)=C1
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Chemical NameBenzonitrile, 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-2,3-dihydro-3-hydroxy-1,1-dioxidobenzo[b]thien-5-yl]oxy]-5-fluoro-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bruick Richard Keith, et al. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414.
2. Dixon Darryl David, et al. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625.
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