Cart
sales@molnova.com
CJ-13610
CAS No. 179420-17-8
CJ-13610( CJ13610 )
Catalog No. M12705 CAS No. 179420-17-8
CJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 82 | Get Quote |
|
| 10MG | 142 | Get Quote |
|
| 25MG | 314 | Get Quote |
|
| 50MG | 530 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCJ-13610
-
NoteResearch use only, not for human use.
-
Brief DescriptionCJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM.
-
DescriptionCJ-13610 is a potent 5-Lipoxygenase (5-LO) inhibitor that suppresses 5-LO product formation with IC50 of 70 nM; demonstrates antihyperalgesic activity in inflammatory pain models including the acute carrageenan model and the chronic inflammatory model.Asthma Phase 2 Discontinued.
-
In Vitro——
-
In Vivo——
-
SynonymsCJ13610
-
PathwayImmunology/Inflammation
-
TargetLipoxygenase
-
RecptorLipoxygenase
-
Research AreaInflammation/Immunology
-
IndicationAsthma
Chemical Information
-
CAS Number179420-17-8
-
Formula Weight393.505
-
Molecular FormulaC22H23N3O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 10 mg/mL (25.41 mM)
-
SMILESO=C(C1(C2=CC=CC(SC3=CC=C(N4C=CN=C4C)C=C3)=C2)CCOCC1)N
-
Chemical Nametetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fischer L, et al. Br J Pharmacol. 2004 Jul;142(5):861-8.
2. Cortes-Burgos LA, et al. Eur J Pharmacol. 2009 Sep 1;617(1-3):59-67.
3. von Knethen A, et al. Cell Signal. 2013 Dec;25(12):2762-8.
molnova catalog
related products
-
5-LOX-IN-1
5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
-
Atreleuton
Atreleuton (ABT-761) is a selective, reversible, and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor.
-
12R-LOX-IN-2
12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.
