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UNC-2170

CAS No. 1648707-58-7

UNC-2170( UNC2170 )

Catalog No. M12518 CAS No. 1648707-58-7

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	52	In Stock
5MG	39	In Stock
10MG	65	In Stock
25MG	141	In Stock
50MG	207	In Stock
100MG	294	In Stock
200MG	405	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

UNC-2170
Note

Research use only, not for human use.
Brief Description

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
Description

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain; is highly cell permeant with no significant measureable cellular efflux; shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
In Vitro

——
In Vivo

——
Synonyms

UNC2170
Pathway

Apoptosis
Target

MDM2-p53
Recptor

MDM2-p53
Research Area

——
Indication

——

Chemical Information

CAS Number

1648707-58-7
Formula Weight

313.23
Molecular Formula

C14H21BrN2O
Purity

>98% (HPLC)
Solubility

In Vitro:?Methanol : 125 mg/mL (399.07 )
SMILES

CC(C)(C)NCCCNC(=O)C1=CC(=CC=C1)Br.C(=CC(=O)O)C(=O)O
Chemical Name

3-bromo-N-(3-(tert-butylamino)propyl)benzamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.

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