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PWZ-029
CAS No. 164025-33-6
PWZ-029( PWZ029 )
Catalog No. M12484 CAS No. 164025-33-6
PWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePWZ-029
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NoteResearch use only, not for human use.
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Brief DescriptionPWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM.
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DescriptionPWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM, demonstrates memory enhancing effects in vivo; successfully reverses the 0.3 mg/kg scopolamine-induced deficit in recognition memory at 2 mg/kg dose with no effect on anxiety or muscle tone.
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In Vitro——
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In Vivo——
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SynonymsPWZ029
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGAT
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Research Area——
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Indication——
Chemical Information
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CAS Number164025-33-6
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Formula Weight291.735
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Molecular FormulaC14H14ClN3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N(C)CC2=C(COC)N=CN2C3=CC=C(Cl)C=C13
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Chemical Name8-chloro-3-(methoxymethyl)-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Savi? MM, et al. Brain Res. 2008 May 7;1208:150-9.
2. Mili? M, et al. Behav Brain Res. 2013 Mar 15;241:206-13.
3. Soto PL, et al. Neuropsychopharmacology. 2013 Oct;38(11):2315-25.
4. Timi? Stameni? T, et al. J Psychopharmacol. 2015 Sep;29(9):1013-24.
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