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K-Ras G12C-IN-2

CAS No. 1629267-75-9

K-Ras G12C-IN-2( —— )

Catalog No. M12442 CAS No. 1629267-75-9

A novel and irreversible inhibitor of mutant K-ras G12C.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    K-Ras G12C-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel and irreversible inhibitor of mutant K-ras G12C.
  • Description
    A novel and irreversible inhibitor of mutant K-ras G12C.
  • In Vitro
    K-Ras G12C-IN-2 is a covalent kras g12c inhibitor extracted from patent WO2014152588A1, compound V-35.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    Ras
  • Recptor
    Ras
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1629267-75-9
  • Formula Weight
    418.9171
  • Molecular Formula
    C21H27ClN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 22 mg/mL
  • SMILES
    C=CC(=O)N1CC(C1)N2CCN(CC2)C(=O)CNC3=C(C=C(C(=C3)C4CC4)Cl)O
  • Chemical Name
    2-Propen-1-one, 1-[3-[4-[2-[(4-chloro-5-cyclopropyl-2-hydroxyphenyl)amino]acetyl]-1-piperazinyl]-1-azetidinyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. From PCT Int. Appl. (2014), WO 2014152588 A1 20140925.
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