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K-Ras G12C-IN-1

CAS No. 1629265-17-3

K-Ras G12C-IN-1( —— )

Catalog No. M12441 CAS No. 1629265-17-3

A novel and irreversible inhibitor of mutant K-ras G12C.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

K-Ras G12C-IN-1
Note

Research use only, not for human use.
Brief Description

A novel and irreversible inhibitor of mutant K-ras G12C.
Description

A novel and irreversible inhibitor of mutant K-ras G12C.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

Ras
Recptor

Ras
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

1629265-17-3
Formula Weight

448.3423
Molecular Formula

C22H23Cl2N3O3
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 40 mg/mL
SMILES

COC1=C(C=C(C(=C1)Cl)C2=CC=CC=C2Cl)NCC(=O)N3CCN(CC3)C(=O)C=C
Chemical Name

2-Propen-1-one, 1-[4-[2-[(2',6-dichloro-4-methoxy[1,1'-biphenyl]-3-yl)amino]acetyl]-1-piperazinyl]-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. From PCT Int. Appl. (2014), WO 2014152588 A1 20140925.

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