BW-723C86( BW 723C86 | BW723C86 )

Catalog No. M12306 CAS No. 160521-72-2

A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

BW-723C86
Note

Research use only, not for human use.
Brief Description

A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes.
Description

A potent, selective 5-HT2B receptor agonist with pKi of 7.1, >10-fold selectivity over 5-HT2A, 5-HT2C, and other 5-HT subtypes; exerts an appreciable anxiolytic-like profile in a rat social interaction test, causes hyperphagia and reduced grooming in rats.Anxiety Preclinical.
In Vitro

——
In Vivo

——
Synonyms

BW 723C86 | BW723C86
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Neurological Disease
Indication

Anxiety

Chemical Information

CAS Number

160521-72-2
Formula Weight

322.85
Molecular Formula

C16H18N2OS.HCl
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (309.74 mM)
SMILES

NC(C)CC1=CNC2=C1C=C(OCC3=CC=CS3)C=C2.[H]Cl
Chemical Name

α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kennett GA, et al. Neuropharmacology. 1997 Feb;36(2):233-9. 2. Kennett GA, et al. Br J Pharmacol. 1996 Apr;117(7):1443-8. 3. Ellis ES, et al. Br J Pharmacol. 1995 Jan;114(2):400-4.

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