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(Rac)-WAY-161503
CAS No. 75704-24-4
(Rac)-WAY-161503( —— )
Catalog No. M33171 CAS No. 75704-24-4
(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor [Ki: 4 nM; EC50: 12 nM], exhibiting anti-obesity and antidepressant effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 82 | In Stock |
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| 10MG | 113 | In Stock |
|
| 25MG | 182 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | 386 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(Rac)-WAY-161503
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NoteResearch use only, not for human use.
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Brief Description(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor [Ki: 4 nM; EC50: 12 nM], exhibiting anti-obesity and antidepressant effects.
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Description(Rac)-WAY-161503 is a potent, selective, highly affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.
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In Vitro——
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In VivoAnimal Model:Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Dose-dependently decreased locomotor activity, an effect that was blocked by the 5-HT2C/2B antagonist SER-082.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number75704-24-4
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Formula Weight272.13
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Molecular FormulaC11H11Cl2N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (367.47 mM; Ultrasonic )
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SMILESClc1cc2NC(=O)C3CNCCN3c2cc1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Halberstadt AL, et al. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology. 2009 Jul;34(8):1958-67.?
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