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Capecitabine

CAS No. 154361-50-9

Capecitabine( Ro 09-1978 )

Catalog No. M12189 CAS No. 154361-50-9

Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 46 In Stock
100MG Get Quote In Stock
200MG 29 In Stock
500MG 43 In Stock
1G 58 In Stock
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Biological Information

  • Product Name
    Capecitabine
  • Note
    Research use only, not for human use.
  • Brief Description
    Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
  • Description
    Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Ro 09-1978
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Thymidine phosphorylase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    154361-50-9
  • Formula Weight
    359.35
  • Molecular Formula
    C15H22FN3O6
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 72 mg/mL (200.36 mM); Water: 6 mg/mL (16.69 mM); DMSO: 72 mg/mL (200.36 mM)
  • SMILES
    O=C(OCCCCC)NC(C(F)=CN1[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)=NC1=O
  • Chemical Name
    pentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lv H, et al. Chin J Y Res. 2014 Dec; 26(6):692-7.
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