Omuralide

CAS No. 154226-60-5

Omuralide( Clasto-lactacystin )

Catalog No. M12183 CAS No. 154226-60-5

A potent 20S proteasome inhibitor with IC50 of 49 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Omuralide
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent 20S proteasome inhibitor with IC50 of 49 nM.
  • Description
    A potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Clasto-lactacystin
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Proteasome
  • Recptor
    Proteasome
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    154226-60-5
  • Formula Weight
    213.233
  • Molecular Formula
    C10H15NO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N[C@@]12[C@@H](O)C(C)C)[C@H](C)[C@]2([H])OC1=O
  • Chemical Name
    (1R,4R,5S)-1-[(1S)-1-Hydroxy-2-methylpropyl]-4-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Corey EJ, et al. Chem Pharm Bull (Tokyo). 1999 Jan;47(1):1-10. 2. List A, et al. Angew Chem Int Ed Engl. 2014 Jan 7;53(2):571-4. 3. Feling RH, et al. Angew Chem Int Ed Engl. 2003 Jan 20;42(3):355-7.
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