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Dantrolene sodium

CAS No. 14663-23-1

Dantrolene sodium( F 440 )

Catalog No. M11997 CAS No. 14663-23-1

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 30 In Stock
100MG 42 In Stock
200MG 51 In Stock
500MG 84 In Stock
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Biological Information

  • Product Name
    Dantrolene sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors.
  • Description
    A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors; can prevent cell death in neural progenitor cells derived from Wolfram syndrome iPS cells.Other Indication Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    F 440
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    CalciumChannel|Ryanodinereceptor1
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    14663-23-1
  • Formula Weight
    336.2348
  • Molecular Formula
    C14H9N4NaO5
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1C(=O)N=C(N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]
  • Chemical Name
    2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lu S, et al. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5292-301. 2. Zucchi R, et al. Pharmacol Rev. 1997 Mar;49(1):1-51. 3. Krause T, et al. Anaesthesia. 2004 Apr;59(4):364-73.
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