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Dantrolene sodium

CAS No. 14663-23-1

Dantrolene sodium( F 440 )

Catalog No. M11997 CAS No. 14663-23-1

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
50MG 31 In Stock
100MG 44 In Stock
200MG 53 In Stock
500MG 86 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Dantrolene sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors.
  • Description
    A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors; can prevent cell death in neural progenitor cells derived from Wolfram syndrome iPS cells.Other Indication Approved.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    F 440
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    CalciumChannel|Ryanodinereceptor1
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    14663-23-1
  • Formula Weight
    336.2348
  • Molecular Formula
    C14H9N4NaO5
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1C(=O)N=C(N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]
  • Chemical Name
    2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lu S, et al. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5292-301. 2. Zucchi R, et al. Pharmacol Rev. 1997 Mar;49(1):1-51. 3. Krause T, et al. Anaesthesia. 2004 Apr;59(4):364-73.
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