Tetomilast( OPC-6535 )

Catalog No. M11976 CAS No. 145739-56-6

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Tetomilast
Note

Research use only, not for human use.
Brief Description

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions.
Description

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release; attenuates sepsis-induced acute lung injury.COPD Phase 2 Clinical.
In Vitro

——
In Vivo

——
Synonyms

OPC-6535
Pathway

Angiogenesis
Target

PDE
Recptor

PDE
Research Area

Inflammation/Immunology
Indication

COPD

Chemical Information

CAS Number

145739-56-6
Formula Weight

370.42
Molecular Formula

C19H18N2O4S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(C1=NC(C2=CSC(C3=CC=C(OCC)C(OCC)=C3)=N2)=CC=C1)O
Chemical Name

6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Schreiber S, et al. Gastroenterology. 2007 Jan;132(1):76-86. 2. Bloomfield GL, et al. J Surg Res. 1997 Sep;72(1):70-7. 3. Ejiri S, et al. Transplant Proc. 2000 Mar;32(2):318-21.

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