PU-H54

CAS No. 1454619-13-6

PU-H54( PU H 54 )

Catalog No. M11959 CAS No. 1454619-13-6

A potent, selective Grp94 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 69 In Stock
10MG 112 In Stock
25MG 259 In Stock
50MG 375 In Stock
100MG 533 In Stock
200MG 724 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PU-H54
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective Grp94 inhibitor.
  • Description
    A potent, selective Grp94 inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PU H 54
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1454619-13-6
  • Formula Weight
    337.45
  • Molecular Formula
    C18H19N5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (296.35 mM)
  • SMILES
    CC1=CC(C)=C(SC2=NC3=C(N)N=CN(CCCC#C)C3=N2)C=C1
  • Chemical Name
    8-((2,4-dimethylphenyl)thio)-3-(pent-4-yn-1-yl)-3H-purin-6-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018. 2. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.
molnova catalog
related products
  • Hexamethylene amilor...

    HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 μM). It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 μM for various NHE isoforms.

  • HSP70 modulator 115-...

    HSP70 modulator 115-7c is an artificial co-chaperone, enhancer of Hsp70.

  • 17-AAG hydrochloride

    A potent Hsp90 inhibitor with IC50 of 5 nM in cell-free assays.