PROTAC-VHL-ligand( —— )

Catalog No. M11915 CAS No. 1448297-52-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

PROTAC-VHL-ligand
Note

Research use only, not for human use.
Brief Description

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
Description

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

E3 Ligase Ligand
Recptor

E3 Ligase Ligand
Research Area

Other Indications
Indication

——

CAS Number

1448297-52-6
Formula Weight

430.567
Molecular Formula

C22H30N4O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (232.26 mM)
SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)N)O
Chemical Name

L-Prolinamide,3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-,(4R)-

1. Bondeson DP, et al. Nat Chem Biol. 2015 Aug;11(8):611-7.

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