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BR103

CAS No. 1434873-26-3

BR103( BR 103 )

Catalog No. M11848 CAS No. 1434873-26-3

BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

BR103
Note

Research use only, not for human use.
Brief Description

BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM.
Description

BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats.
In Vitro

——
In Vivo

——
Synonyms

BR 103
Pathway

Immunology/Inflammation
Target

Complement System
Recptor

Complement System
Research Area

——
Indication

——

Chemical Information

CAS Number

1434873-26-3
Formula Weight

448.527
Molecular Formula

C24H28N6O3
Purity

>98% (HPLC)
Solubility

——
SMILES

N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(C)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=N1)=O
Chemical Name

(2-benzhydryl-5-methyl-1H-imidazole-4-carbonyl)-L-arginine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351.

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