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Eletriptan
CAS No. 143322-58-1
Eletriptan( UK 116044 )
Catalog No. M11842 CAS No. 143322-58-1
Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 314 | In Stock |
|
| 10MG | 464 | In Stock |
|
| 25MG | 1074 | In Stock |
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| 50MG | 1841 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEletriptan
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NoteResearch use only, not for human use.
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Brief DescriptionEletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist.
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DescriptionEletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist; significantly increases occluded wedge pressure and mean pulmonary artery pressure in vivo, with no significant coronary artery constriction, and obstructive coronary artery disease; displays antimigraine activity.Migraine Approved.
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In Vitro——
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In VivoEletriptan (10, 30, 100, 300 and 1000 μg/kg; i.v.) reduces total carotid blood flow in anaesthetised pigs by selectively reducing carotid arteriovenous anastomotic blood flow and increasing nutrient blood flow within the carotid vascular bed.
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SynonymsUK 116044
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationMigraine
Chemical Information
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CAS Number143322-58-1
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Formula Weight382.52
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Molecular FormulaC22H26N2O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCC[C@@H]1Cc2c[nH]c3c2cc(cc3)CCS(=O)(=O)c4ccccc4
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Chemical Name3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Napier C, et al. Eur J Pharmacol. 1999 Mar 5;368(2-3):259-68.
2. Gupta P, et al. Eur J Pharmacol. 1999 Feb 19;367(2-3):283-90.
3. Muir DF, et al. Clin Pharmacol Ther. 1999 Jul;66(1):85-90.
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