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Filaminast
CAS No. 141184-34-1
Filaminast( WAY-PDA-641 | PDA-641 | WAY-123641 )
Catalog No. M11714 CAS No. 141184-34-1
Filaminast (WAY-PDA-641;PDA-641;WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 351 | In Stock |
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| 5MG | 387 | In Stock |
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| 10MG | 514 | In Stock |
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| 25MG | 778 | In Stock |
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| 50MG | 1014 | In Stock |
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| 100MG | 1367 | In Stock |
|
| 200MG | 1851 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFilaminast
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NoteResearch use only, not for human use.
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Brief DescriptionFilaminast (WAY-PDA-641;PDA-641;WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
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DescriptionFilaminast (WAY-PDA-641;PDA-641;WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3; significantly potentiates the relaxant effects of albuterol, reverses tracheal contractions induced by prostaglandin F2 alpha, leukotriene D4 or histamine in a biphasic manner.Asthma Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsWAY-PDA-641 | PDA-641 | WAY-123641
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research AreaInflammation/Immunology
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IndicationAsthma
Chemical Information
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CAS Number141184-34-1
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Formula Weight292.335
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Molecular FormulaC15H20N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESC(\C)(=N/OC(=O)N)c1cc(c(cc1)OC)OC1CCCC1
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Chemical Name1-(3-(Cyclopentyloxy)-4-methoxyphenyl)ethanone-(E)-O-(aminocarbonyl)oxime
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Heaslip RJ, et al. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.
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