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KPT-185
CAS No. 1333151-73-7
KPT-185( —— )
Catalog No. M11326 CAS No. 1333151-73-7
KPT-185 is a selective CRM1 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameKPT-185
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NoteResearch use only, not for human use.
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Brief DescriptionKPT-185 is a selective CRM1 inhibitor.
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DescriptionKPT-185 is a selective CRM1 inhibitor.
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In VitroCell Viability Assay Cell Line:HPB-ALL, Jurkat, CCRF-CEM, MOLT-4, KOPTK1, LOUCY cells Concentration:1, 10, 100, 1000 nM Incubation Time:72 hours Result:The growth of those lines was dramatically reduced with IC50s of 16–395 nM after 72 h of exposure.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetCRM1
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RecptorCRM1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1333151-73-7
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Formula Weight355.31
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Molecular FormulaC16H16F3N3O3
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Purity>98% (HPLC)
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SolubilityEthanol: 71 mg/mL (199.82 mM); DMSO: 71 mg/mL (199.82 mM)
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SMILESCC(C)OC(=O)/C=C\N1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ranganathan P, et al. Blood. 2012, 120(9), 1765-1773.
molnova catalog
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