ORM-15341( —— )

Catalog No. M11200 CAS No. 1297537-33-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

ORM-15341
Note

Research use only, not for human use.
Brief Description

The active main metabolite of ODM-201, a potent wt/mutant androgen receptor (AR) inhibitor.
Description

The active main metabolite of ODM-201, a potent wt/mutant androgen receptor (AR) inhibitor; inhibits wtAR/AR(F876L) with IC50s of 25/51 nM respectively; suppresses androgen-induced cell proliferation more efficaciously than enzalutamide or ARN-509.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Androgen Receptor (AR)
Recptor

Androgen Receptor (AR)
Research Area

Endocrinology
Indication

——

CAS Number

1297537-33-7
Formula Weight

396.8303
Molecular Formula

C19H17ClN6O2
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 37 mg/mL
SMILES

CC(CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=CC(=NN3)C(=O)C
Chemical Name

1H-Pyrazole-3-carboxamide, 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-

1. Moilanen AM, et al. Sci Rep. 2015 Jul 3;5:12007.

Calculator

molnova catalog