GS967( GS967 | GS-967 | GS 967 | GS458967 )

Catalog No. M11095 CAS No. 1262618-39-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

GS967
Note

Research use only, not for human use.
Brief Description

GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa).
Description

GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late INa); inhibits ATX-II-induced late I(Na) in ventricular myocytes and isolated hearts with IC(50) values of 0.13 and 0.21 μM, respectively.
In Vitro

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In Vivo

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Synonyms

GS967 | GS-967 | GS 967 | GS458967
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

late?INa?,isolated hearts| late?INa?,ventricular myocytes
Research Area

Cardiovascular Disease
Indication

——

CAS Number

1262618-39-2
Formula Weight

347.22
Molecular Formula

C14H7F6N3O
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

FC(C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21)(F)F
Chemical Name

6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)(1,2,4)triazolo(4,3-a)pyridine

1.Belardinelli L, et al. J Pharmacol Exp Ther. 2013 Jan;344(1):23-32.

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