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Ralfinamide
CAS No. 133865-88-0
Ralfinamide( FCE-26742A | Priralfinamide )
Catalog No. M20711 CAS No. 133865-88-0
Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 31 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 59 | In Stock |
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| 50MG | 107 | In Stock |
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| 100MG | 164 | In Stock |
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| 200MG | 242 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameRalfinamide
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NoteResearch use only, not for human use.
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Brief DescriptionRalfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
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DescriptionRalfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.(In Vivo):Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain.
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In Vitro——
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In VivoRalfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g)Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42Result:Suppressed neuropathic pain.
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SynonymsFCE-26742A | Priralfinamide
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorNa-channel
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Research AreaNeurological Disease
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IndicationNeuropathic pain
Chemical Information
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CAS Number133865-88-0
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Formula Weight302.34
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Molecular FormulaC17H19FN2O2
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (413.44 mM)
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SMILESC[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
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Chemical Name(2S)-2-(4-(2-Fluorobenzyloxy)benzylamino)propanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.
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