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TBA-354
CAS No. 1257426-19-9
TBA-354( TBA354 )
Catalog No. M11059 CAS No. 1257426-19-9
TBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 39 | In Stock |
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| 25MG | 74 | In Stock |
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| 50MG | 116 | In Stock |
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| 100MG | 187 | In Stock |
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| 200MG | 272 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTBA-354
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NoteResearch use only, not for human use.
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Brief DescriptionTBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv.
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DescriptionTBA-354 is a novel antitubercular agent that shows MIC of 6 uM against M. tuberculosis H37Rv; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates, demonstrates superior potency and pharmacokinetic profile compared with PA-824, 5 to 10 times more potent than PA-824.Bacterial Infection Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsTBA354
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorOthers
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number1257426-19-9
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Formula Weight436.3414
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Molecular FormulaC19H15F3N4O5
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 46 mg/mL
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SMILESO=[N+](C1=CN2C(OC[C@@H](OCC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)N=C3)C2)=N1)[O-]
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Chemical Name5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[6-[4-(trifluoromethoxy)phenyl]-3-pyridinyl]methoxy]-, (6S)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kmentova I, et al. J Med Chem. 2010 Dec 9;53(23):8421-39.
2. Upton AM, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
3. Tasneen R, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
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