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BRPF1B TRIM24-IN-34
CAS No. 1242907-48-7
BRPF1B TRIM24-IN-34( —— )
Catalog No. M10983 CAS No. 1242907-48-7
BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBRPF1B TRIM24-IN-34
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NoteResearch use only, not for human use.
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Brief DescriptionBRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively.
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DescriptionBRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively; exhibits good selectivity over other bromodomains; showes no significant cytotoxicity in a panel of cancer cell lines (GI50>10 uM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number1242907-48-7
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Formula Weight499.538
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Molecular FormulaC24H25N3O7S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3,4-dimethoxy-N-(6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bennett J, et al. J Med Chem. 2016 Feb 25;59(4):1642-7.
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