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SRTCX1002
CAS No. 1203479-63-3
SRTCX1002( SRTCX-1002 )
Catalog No. M10742 CAS No. 1203479-63-3
SRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSRTCX1002
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NoteResearch use only, not for human use.
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Brief DescriptionSRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM.
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DescriptionSRTCX1002 (SRTCX-1002) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.4 uM, enhances deacetylation of cellular p65 protein with IC50 of 0.84 uM in cellular p65 acetylation assay; suppresses TNFα-induced NF-κB transcriptional activation and reduction of LPS-stimulated TNFα secretion in a SIRT1-dependent manner.
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In Vitro——
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In Vivo——
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SynonymsSRTCX-1002
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research Area——
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Indication——
Chemical Information
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CAS Number1203479-63-3
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Formula Weight405.476
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Molecular FormulaC21H19N5O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=C2NC(C3=CC=CC(N4CCOCC4)=C3)=NC2=CC=C1)NC5=NC=CS5
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Chemical Name2-[3-(4-Morpholinyl)phenyl]-N-2-thiazolyl-1H-benzimidazole-7-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yang H, et al. PLoS One. 2012;7(9):e46364.
2. Kim SY, et al. PLoS One. 2015 Jul 15;10(7):e0133448.
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