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SIRT5 inhibitor 1
CAS No. 2166487-21-2
SIRT5 inhibitor 1( —— )
Catalog No. M33124 CAS No. 2166487-21-2
SIRT5 inhibitor 1 is a potent and selective inhibitor of human Sirtuin 5 deacylase (IC50: 0.11 μM) and is associated with aging-related diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 466 | In Stock |
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| 2MG | 207 | In Stock |
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| 5MG | 353 | In Stock |
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| 10MG | 530 | In Stock |
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| 25MG | 934 | In Stock |
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| 50MG | 1330 | In Stock |
|
| 100MG | 1786 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSIRT5 inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionSIRT5 inhibitor 1 is a potent and selective inhibitor of human Sirtuin 5 deacylase (IC50: 0.11 μM) and is associated with aging-related diseases.
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DescriptionSIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
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In VitroSIRT5 inhibitor 1 (compound 49) is a very potent human sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1.
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research Area——
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Indication——
Chemical Information
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CAS Number2166487-21-2
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Formula Weight674.81
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Molecular FormulaC31H39FN6O6S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (185.24 mM; Ultrasonic )
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SMILESOC(=O)CCNC(=S)NCCCC[C@H](NS(=O)(=O)c1cccc(F)c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC1CCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.?
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