Cart
sales@molnova.com
Home - Products - GPCR/G Protein - 5-HT Receptor - SB 206553

SB 206553

CAS No. 1197334-04-5

SB 206553( SB206553 )

Catalog No. M10703 CAS No. 1197334-04-5

SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 963 Get Quote
50MG 1962 Get Quote
100MG 2520 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SB 206553
  • Note
    Research use only, not for human use.
  • Brief Description
    SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
  • Description
    SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes; exhibits anxiolytic-like properties both in vitro and in vivo.Anxiety Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SB206553
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Anxiety

Chemical Information

  • CAS Number
    1197334-04-5
  • Formula Weight
    328.8
  • Molecular Formula
    C17H16N4O.HCl
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl
  • Chemical Name
    3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Forbes IT, et al. J Med Chem. 1995 Jul 7;38(14):2524-30. 2. Upton N, et al. Eur J Pharmacol. 1998 Oct 16;359(1):33-40. 3. Kennett GA, et al. Br J Pharmacol. 1996 Feb;117(3):427-434. 4. Porras G, et al. Neuropsychopharmacology. 2002 Mar;26(3):311-24.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • 3-Hydroxy agomelatin...

    3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

  • Liafensine

    Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders.

  • Lesopitron HCl

    Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.

Sign In Join Free