5-Carboxamidotryptamine maleate( —— )

Catalog No. M33825 CAS No. 74885-72-6

5-Carboxamidotryptamine maleate (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	77	In Stock
10MG	122	In Stock
25MG	218	In Stock
50MG	299	In Stock
100MG	412	In Stock
200MG	573	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

5-Carboxamidotryptamine maleate
Note

Research use only, not for human use.
Brief Description

5-Carboxamidotryptamine maleate (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.
Description

5-Carboxamidotryptamine maleate (5-CT maleate) is a potent 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5 and 5-HT7 receptors agonist.
In Vitro

[3H]-5-Carboxamidotryptamine (5-CT)binding to 5-HT1D sites in bovine substantia nigra is rapid, reversible and saturable, displaying high affinity (Kd = 0.38 nM) and low non-specific binding. In bovine substantia nigra, [3H]-5-Carboxamidotryptamine (5-CT) labelled an equivalent number of binding sites to [3H]-5-Carboxamidotryptamine (403 and 362 fmol/mg protein, respectively) and binding is sensitive to guanine nucleotides.
In Vivo

Topical 5-Carboxamidotryptamine (0.01-1000 μM) to the exposed dura mater encephala produced decreases in diastolic blood pressure, variable changes in meningeal blood flow and increases in conductance (i.e. dilatation) in the middle meningeal artery of anesthetized Wistar rats (serotonin depletion and treated with 20 mg/kg corticosterone).
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

74885-72-6
Formula Weight

319.31
Molecular Formula

C15H17N3O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (156.59 mM; Ultrasonic )H2O : 25 mg/mL (78.29 mM; Ultrasonic)
SMILES

C(=C\C(O)=O)\C(O)=O.C(CN)C=1C=2C(NC1)=CC=C(C(N)=O)C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. E Martínez-García, et al. 5-HT7 receptor-mediated meningeal dilatation induced by 5-carboxamidotryptamine in rats is not altered by 5-HT depletion and chronic corticosterone treatment. Proc West Pharmacol Soc. 2011;54:57-61.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks