Clopidogrel thiolactone( 2-Oxo-clopidogrel | Clopidogrel thiolactone | 2-Oxoclopidogrel )

Catalog No. M10522 CAS No. 1147350-75-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Clopidogrel thiolactone
Note

Research use only, not for human use.
Brief Description

A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets.
Description

A thienopyridine-class antiplatelet agent that works by irreversibly inhibiting P2Y12 receptor on platelets; used to reduce the risk of heart disease and stroke in those at high risk.Thrombosis Approved.
In Vitro

——
In Vivo

Clopidogrel thiolactone (8 μm/kg; i.v.; Sprague-Dawley male rats) has good biological availability and pharmacokinetic parameters. Animal Model:Sprague-Dawley male ratsDosage:8 μm/kg; orally clopidogrel (24 μm/kg)Administration:Intravenous injection; collected blood at 0 h (before dosing) and 0.083, 0.167, 0.5, 1, 2, 4, 6, 8, 24 h postdose.
Synonyms

2-Oxo-clopidogrel | Clopidogrel thiolactone | 2-Oxoclopidogrel
Pathway

GPCR/G Protein
Target

P2Y Receptor
Recptor

P2Y Receptor
Research Area

Cardiovascular Disease
Indication

Thrombosis

CAS Number

1147350-75-1
Formula Weight

337.8211
Molecular Formula

C16H16ClNO3S
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

O=C(OC)[C@H](C1=CC=CC=C1Cl)N2CCC3C(C2)=CC(S3)=O
Chemical Name

Thieno[3,2-c]pyridine-5(4H)-acetic acid, a-(2-chlorophenyl)-2,6,7,7a-tetrahydro-2-oxo-, methyl ester, (aS)-